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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
9.7
Human Site:
T635
Identified Species:
21.33
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
T635
T
V
T
N
R
S
S
T
D
T
A
S
I
F
G
Chimpanzee
Pan troglodytes
XP_523109
766
83908
T750
T
V
T
N
R
S
S
T
D
T
A
S
I
F
G
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
D627
V
T
N
R
S
S
T
D
T
A
S
I
F
G
I
Dog
Lupus familis
XP_535524
651
71773
T635
T
V
A
N
R
S
S
T
D
T
A
S
I
F
G
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
A635
G
V
A
S
R
S
S
A
D
T
A
S
I
F
G
Rat
Rattus norvegicus
O70260
628
68345
S613
G
H
G
G
P
L
P
S
G
P
S
L
T
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
V734
R
E
N
H
G
H
P
V
A
N
R
S
G
T
D
Chicken
Gallus gallus
NP_001026627
564
62782
S549
L
D
F
F
P
F
L
S
G
D
N
Q
P
A
R
Frog
Xenopus laevis
NP_001079161
649
71676
D634
A
P
S
R
G
P
A
D
S
S
S
L
Y
G
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
F728
M
I
N
Q
A
P
H
F
Q
M
Q
N
G
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
D663
L
G
L
F
N
D
D
D
E
F
D
T
P
L
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
73.3
0
N.A.
6.6
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
80
13.3
N.A.
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
10
0
10
10
10
10
37
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
10
10
28
37
10
10
0
0
0
10
% D
% Glu:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
10
19
0
10
0
10
0
10
0
0
10
37
0
% F
% Gly:
19
10
10
10
19
0
0
0
19
0
0
0
19
28
37
% G
% His:
0
10
0
10
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
10
37
0
28
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
10
0
0
10
10
0
0
0
0
19
0
19
0
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
28
28
10
0
0
0
0
10
10
10
0
0
0
% N
% Pro:
0
10
0
0
19
19
19
0
0
10
0
0
19
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
10
10
0
0
0
% Q
% Arg:
10
0
0
19
37
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
0
0
10
10
10
46
37
19
10
10
28
46
0
0
0
% S
% Thr:
28
10
19
0
0
0
10
28
10
37
0
10
10
10
0
% T
% Val:
10
37
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _